What Is Ivermectin?
Ivermectin is an antiparasitic medication used in humans to treat various parasitic infections such as:
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Intestinal strongyloidiasis
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Onchocerciasis (river blindness)
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Scabies
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Head lice
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Lymphatic filariasis
It belongs to a class of medications called anthelmintics, and works by paralyzing and killing parasites. Originally developed for veterinary use, Ivermectin has been widely adopted in human medicine and is considered an essential drug by the World Health Organization (WHO).
How Does Ivermectin Work?
Ivermectin works by binding to glutamate-gated chloride channels in the nerve and muscle cells of invertebrates. This increases the permeability of cell membranes to chloride ions, resulting in:
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Paralysis
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Disruption of neural function
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Death of the parasite
This mechanism is effective against a wide variety of parasitic organisms but has minimal effects on human cells due to differences in nervous system structure.
Benefits of Ivermectin
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Broad-spectrum antiparasitic: Effective against several parasitic worms, mites, and insects.
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Single-dose convenience: Often requires only one or two doses for certain infections.
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Global availability: Included in many global health programs for mass deworming.
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Well-studied and trusted: Approved by FDA and WHO for specific human use cases.
Administration Tips:
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Take Ivermectin on an empty stomach, with a full glass of water.
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Do not chew or crush the tablet.
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Avoid alcohol and other medications that may affect liver enzymes without consulting a doctor.
Who Makes Ivermectin?
Multiple pharmaceutical companies manufacture Ivermectin worldwide under various brand names. Some of the well-known manufacturers include:
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Merck & Co. – Original developers of Ivermectin (as Stromectol)
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Sun Pharma
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Cipla
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Intas Pharmaceuticals
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Mylan
These manufacturers produce both branded and generic versions of Ivermectin in varying strengths.
Is Ivermectin Safe for Humans?
Yes, Ivermectin is considered safe for human use when taken at the correct dosage and for approved conditions. However, certain precautions must be followed:
Who Should Avoid Ivermectin?
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Pregnant or breastfeeding women (unless advised by a doctor)
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Children under 15 kg
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People with liver or kidney disease
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Those taking medications that interact with liver enzymes (like warfarin or anticonvulsants)
Note: Off-label use (e.g., for COVID-19) is not recommended without medical supervision and has not been proven safe or effective by regulatory authorities like the FDA.
Side Effects of Ivermectin
Most people tolerate Ivermectin well, but some may experience side effects.
Common Side Effects:
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Nausea or vomiting
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Dizziness or drowsiness
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Diarrhea
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Fatigue
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Headache
Less Common or Serious Effects:
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Allergic reactions (rash, swelling, difficulty breathing)
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Low blood pressure
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Vision changes
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Liver function abnormalities
Seek medical attention immediately if you experience serious side effects.
Disclaimer
This content is for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your physician before starting any new medication, including Ivermectin. Misuse or self-medication can be harmful.
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